Lysosomes take in whole vacuoles that are floating around in the cytoplasm and break them up into smaller pieces that will be easier for the mitochondria to turn into energy. One thing lysosomes break up is captured viruses or bacteria (germs) that have gotten inside the cell and are threatening to destroy it. So if your lysosomes weren't working well, one thing that would happen would be that you would get sick more often, and it would be harder for you to get better.